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簡要描述:positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
產(chǎn)品型號(hào):bs-8306R-Bio
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-03-10
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